Methyl iodide → 3-(3-(3-Pentynyloxy)-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

HRID 256954Notes

Reaction equation

HRID 256954 reaction equation
[CH3:1][I:2].[CH2:3]([O:8][C:9]1[C:10]([C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[N:11][S:12][N:13]=1)[CH2:4][C:5]#[C:6][CH3:7]>CC(C)=O>[I-:2].[CH2:3]([O:8][C:9]1[C:10]([C:14]2[CH:15]=[N+:16]([CH3:1])[CH:17]=[CH:18][CH:19]=2)=[N:11][S:12][N:13]=1)[CH2:4][C:5]#[C:6][CH3:7]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 190752603-(3-(3-Pentynyloxy)-1,2,5-thiadiazol-4-yl)pyridine

Product 1

HCID 190752403-(3-(3-Pentynyloxy)-1,2,5-thiadiazol-4-yl)-1-methylpyridinium iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.6 ml, 9 mmol) and 3-(4-(3-pentynyloxy)-1,2,5-thiadiazol-3-yl) pyridine (3 mmol) in acetone (10 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.68 g (59%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.68 g (59%)

Sources & evidence

ORD record
ord-cd925a1936684902971eddc784973986
Source dataset
uspto-grants-1993_11
Patent number
US05260311

Reaction notes

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