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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 257080Generated: October 26, 2026

1-(4-Nitrophenyl)-4-piperidinol → 1-(4-Aminophenyl)piperidin-4-ol

https://huagongshe.com/reaction/257080

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Nitrophenyl)-4-piperidinolHCID 613768—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
Product1-(4-Aminophenyl)piperidin-4-olHCID 1679210792.5%

Reaction Steps

1.0 g (4.5 mmol) of 1-(4-nitrophenyl)-4-hydroxypiperidine are hydrogenated in a conventional manner with Pd/carbon in methanol. 0.8 g of 1-(4-aminophenyl)-4-hydroxypiperidine is obtained. Melting point 176° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05260318
Source datasetuspto-grants-1993_11
ORD IDord-f91963aa89e94024a3450008cf5bfc51
Source noteuspto-grants-1993_11