HCID 19784370, compound → HCID 19784344, compound

Participants

Reaction Steps

1.2 g (3.3 mmol) of the product from Example 2 were hydrogenated on Pd/C (10%) in 100 ml of tetrahydrofuran and worked up in a conventional manner. 1.1 g of 4-(2-(4-aminophenyl)-N-methylethylamino)-1-(4-cyanophenyl)piperidine were obtained as an oil. 1H NMR (d6 -DMSO) δ=1.2-1.5 (2H); 1.8-1.9 (2H); 2.1 (3H); 2.4-2.7 (4H); 2.7-2.9 (2H); 3.3 (1H); 3.9 (2); 6.4 (2H); 6.8 (2H); 6.9 (2H) and 7.5 (2H) ppm.

Provenance & Evidence