反应详情

2.5 g (11.4 mmol) of 1-(4-nitrophenyl)-4-piperidone, 1.5 g (11.4 mmol) of N-methyl-N-(2-phenylethyl)amine, 0.7 g (11.4 mmol) of acetic acid and 0.7 g (11.4 mmol) of sodium cyanoborohydride were reacted in a similar manner to Example 1. The product was converted into the fumarate with fumaric acid in a conventional manner. 2.8 g of 4-(N-methyl-N-(2-phenylethyl)amino)-1-(4-nitrophenyl)piperidine fumarate were obtained. Melting point 201°-202° C.