Hydrochloric Acid → HCID 19784375, compound

HRID 257087Notes

Reaction equation

HRID 257087 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:13][CH2:12][CH:11]([N:14]([CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH3:15])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.[CH3:23][S:24]([Cl:27])(=[O:26])=[O:25].[ClH:28]>>[ClH:27].[ClH:28].[CH2:16]([N:14]([CH:11]1[CH2:10][CH2:9][N:8]([C:5]2[CH:4]=[CH:3][C:2]([NH:1][S:24]([CH3:23])(=[O:26])=[O:25])=[CH:7][CH:6]=2)[CH2:13][CH2:12]1)[CH3:15])[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 31297Methanesulfonyl chlorideHCID 19784381HCID 19784381, compound

Product 1

HCID 19784375HCID 19784375, compound

Procedure

The product from Example 8 was reacted in a similar manner to Example 4 with methanesulfonyl chloride and then converted into the hydrochloride. 4-(N-Benzyl-N-methylamino)-1-(4-methanesulfonylaminophenyl)piperidine dihydrochloride was obtained. Melting point 221° C. (decomposition).

Sources & evidence

ORD record
ord-df054a58e50540d8863ceda7aa281444
Source dataset
uspto-grants-1993_11
Patent number
US05260318

Reaction notes

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