Dipropylamine → HCID 67862342, compound

HRID 257117Notes

Reaction equation

HRID 257117 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][CH2:9][C:10]([CH3:22])([CH3:21])[CH2:11][CH2:12][CH:13]2[CH2:18][C:17]([CH3:20])([CH3:19])[NH:16][CH2:15][CH2:14]2)[N:5]=[C:4]([NH:23][CH2:24][C:25]([CH3:37])([CH3:36])[CH2:26][CH2:27][CH:28]2[CH2:33][C:32]([CH3:35])([CH3:34])[NH:31][CH2:30][CH2:29]2)[N:3]=1.[CH2:38]([NH:41][CH2:42][CH2:43][CH3:44])[CH2:39][CH3:40].[OH-].[Na+]>C1(C)C(C)=CC=CC=1>[CH2:38]([N:41]([CH2:42][CH2:43][CH3:44])[C:2]1[N:3]=[C:4]([NH:23][CH2:24][C:25]([CH3:37])([CH3:36])[CH2:26][CH2:27][CH:28]2[CH2:33][C:32]([CH3:34])([CH3:35])[NH:31][CH2:30][CH2:29]2)[N:5]=[C:6]([NH:8][CH2:9][C:10]([CH3:22])([CH3:21])[CH2:11][CH2:12][CH:13]2[CH2:18][C:17]([CH3:20])([CH3:19])[NH:16][CH2:15][CH2:14]2)[N:7]=1)[CH2:39][CH3:40]

Participants

5

Reactant 3

HCID 8902DipropylamineHCID 14798Sodium HydroxideHCID 86745645HCID 86745645, compound

Product 1

HCID 67862342HCID 67862342, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

53.6 g of 2-chloro-4,6-bis-(2,2,6,6-tetramethyl-4-piperidylbutylamino)-1,3,5-triazine, together with 15.0 g of dipropylamine in 250 ml of xylene, are stirred under reflux for 16 hours. After cooling to room temperature, 100 ml of 2N sodium hydroxide solution are added, the mixture is stirred vigorously for 15 minutes and the aqueous phase is then separated off. The xylene solution is dried over sodium sulfate and evaporated in vacuo. Crystallisation of the resulting residue from acetonitrile gives 2-dipropylamino-4,6-bis-(2,2,6,6-tetramethyl-4-piperidylbutylamino)-1,3,5-triazine, melting point 95°-96° C.

Workup

  1. temperatureunder reflux for 16 hours
  2. customthe aqueous phase is then separated off
  3. dry with materialThe xylene solution is dried over sodium sulfate
  4. customevaporated in vacuo
  5. customCrystallisation of the resulting residue from acetonitrile

Sources & evidence

ORD record
ord-14bd013415c74df5b8e1cd3131fb8dd9
Source dataset
uspto-grants-1993_11
Patent number
US05260362

Reaction notes

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