2-Benzylthio-3,5-dinitrobenzotrifluoride → 3,5-Diamino-2-benzylthiobenzotrifluoride

HRID 257136Notes

Reaction equation

HRID 257136 reaction equation
[CH2:1]([S:8][C:9]1[C:14]([N+:15]([O-])=O)=[CH:13][C:12]([N+:18]([O-])=O)=[CH:11][C:10]=1[C:21]([F:24])([F:23])[F:22])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>O1CCCC1.[Ni]>[NH2:15][C:14]1[C:9]([S:8][CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[C:10]([C:21]([F:22])([F:23])[F:24])[CH:11]=[C:12]([NH2:18])[CH:13]=1

Participants

4

Reactant 1

HCID 135816002-Benzylthio-3,5-dinitrobenzotrifluoride

Product 1

HCID 200964653,5-Diamino-2-benzylthiobenzotrifluoride

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 8028TetrahydrofuranSolvent

Procedure

3 g of 2-benzylthio-3,5-dinitrobenzotrifluoride in 30 ml of tetrahydrofuran are hydrogenated in a glass hydrogenation apparatus for 22 hours at room temperature, using a total of 3 g of Raney nickel. For working up, the catalyst is removed by filtration and washed with tetrahydrofuran, the filtrate is evaporated, and the residue is directly processed as crude product (brownish liquid).

Workup

  1. customthe catalyst is removed by filtration
  2. washwashed with tetrahydrofuran
  3. customthe filtrate is evaporated

Sources & evidence

ORD record
ord-541304f86eec41b68406811d9e0a8e8d
Source dataset
uspto-grants-1993_11
Patent number
US05260423

Reaction notes

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