HCID 19784716, compound → HCID 19784710, compound

HRID 257196Notes

Reaction equation

HRID 257196 reaction equation
[CH3:1][CH:2]1[CH:9]([CH3:10])[N:8]2[C:4](=[C:5]([CH:23]([CH:25]3C(=O)O[C:28](C)([CH3:32])[O:27][C:26]3=[O:34])[CH3:24])[C:6]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[C:7]2[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:3]1>N1C=CC=CC=1.C(O)C.[Cu]>[CH2:28]([O:27][C:26](=[O:34])[CH2:25][CH:23]([C:5]1[C:6]([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)=[C:7]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[N:8]2[C:4]=1[CH2:3][CH:2]([CH3:1])[CH:9]2[CH3:10])[CH3:24])[CH3:32]

Participants

5

Reactant 1

HCID 19784716HCID 19784716, compound

Product 1

HCID 19784710HCID 19784710, compound

Reagents, catalysts & solvents 3

HCID 702EthanolSolventHCID 1049PyridineSolventHCID 23978CopperSolvent

Procedure

2.5 mmoles of 59b are dissolved in a mixture of 20 ml absolute pyridine and 2 ml of absolute ethanol and upon addition of some copper powder the batch is reacted as described for 60a. Purification is by column chromatography (silica gel, n-hexane/CH2Cl2 2+1) in isolation.

Workup

  1. customis reacted
  2. customPurification

Sources & evidence

ORD record
ord-00063e123b0a458c9544ca7c5c89f04b
Source dataset
uspto-grants-1993_11
Patent number
US05260451

Reaction notes

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