Formaldehyde → HCID 6429813, compound

HRID 257240Notes

Reaction equation

[CH2:1]([C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[CH2:16]=[O:17]>>[CH2:1]([C:9]1[CH:10]=[C:11]([CH:16]=[O:17])[C:12]([OH:15])=[CH:13][CH:14]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

Reactant 2

HCID 712Formaldehyde

HCID 157304-Octylphenol

Product 1

HCID 6429813HCID 6429813, compoundYield 85%

Conditions

Temperature: 98 °C

Procedure

The procedure described in Example 4 was followed, replacing the phenol (48 g) by 4-octylphenol (105 g 0.5 mole). During addition of the paraformaldehyde, the internal temperature was maintained at 95°-98° C. and the reaction mixture was stirred at 98° C. for a further hour. In other respects, the conditions were as described in Example 4. The product, 5-octylsalicylaldehyde, was obtained in 85% yield.

Workup

temperaturethe internal temperature was maintained at 95°-98° C.

Sources & evidence

ORD record: ord-2bb42aa5a41649d8a726326cca3fa785
Source dataset: uspto-grants-1993_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05260487

Reaction notes

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