化工社化工社 化学情報印刷レポート · 研究参考用
Isopropyl iodide → 2-Fluoro-4-isopropoxy-1-nitrobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isopropyl iodide | HCID 6362 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 3-Fluoro-4-nitrophenol | HCID 520948 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 2-Fluoro-4-isopropoxy-1-nitrobenzene | HCID 13538652 | 95.6% |
反応手順
By the method of Example 3, Step A, 23.15 g (0.147 mole) of 3-fluoro-4-nitrophenol and 29.92 g (0.175 mole) of 2-iodopropane were reacted in the presence of 20.73 g (0.150 mole) of anhydrous potassium carbonate in 450 mL of acetone, yielding 28.0 g of 4-isopropoxy-2-fluoronitrobenzene as an oil. The NMR was consistent with the proposed structure.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05262390 |
| 出典データセット | uspto-grants-1993_11 |
| ORD ID | ord-dd66cd547acf42eab2d7601f2c383cc7 |
| 出典メモ | uspto-grants-1993_11 |