4-Ethylpyridine → 1-(2,4-Dichlorophenyl)-3-(4-pyridyl)butane

HRID 257465Notes

Reaction equation

HRID 257465 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)[CH3:2].[Cl:9][C:10]1[CH:18]=[C:17]([Cl:19])[CH:16]=[CH:15][C:11]=1[CH2:12][CH2:13]Br>>[Cl:9][C:10]1[CH:18]=[C:17]([Cl:19])[CH:16]=[CH:15][C:11]=1[CH2:12][CH2:13][CH:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 108224-EthylpyridineHCID 108485102,4-Dichlorophenethyl bromide

Product 1

HCID 197833321-(2,4-Dichlorophenyl)-3-(4-pyridyl)butaneYield 25.6%

Procedure

1.0 g (9.35 mmol) of 4-ethylpyridine and 2.37 g (9.35 mmol) of 2,4-dichlorophenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified to obtain 0.67 g of the desired compound (yield: 25.6%). The resulting compound was identified as 1-(2,4-dichlorophenyl)-3-(4-pyridyl)-butane (hereinafter referred to as compound 9) by the following analytical results.

Workup

  1. customThe reaction product was purified

Sources & evidence

ORD record
ord-985276f4426647a1a82ad766a78c1cc0
Source dataset
uspto-grants-1993_11
Patent number
US05262420

Reaction notes

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