3,4-Dimethylpyridine → 1-Phenyl-4-(3-methyl-4-pyridyl)-butane

HRID 257479Notes

Reaction equation

HRID 257479 reaction equation
[CH3:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH3:8].Br[CH2:10][CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:13]1([CH2:12][CH2:11][CH2:10][CH2:8][C:7]2[CH:6]=[CH:5][N:4]=[CH:3][C:2]=2[CH3:1])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 114173,4-DimethylpyridineHCID 12503(3-Bromopropyl)benzene

Product 1

HCID 148837871-Phenyl-4-(3-methyl-4-pyridyl)-butaneYield 97.2%

Procedure

1.62 g (15.1 mmol) of 3,4-dimethylpyridine and 3.0 g (15.1 mmol) of 1-bromo-3-phenylpropane were reacted in the same manner as in Example 26. The reaction product was purified to obtain 3.3 g of the desired compound (yield: 97.2%). The resulting compound was identified as 1-phenyl-4-(3-methyl-4-pyridyl)-butane (hereinafter referred to as compound 41) by the following analytical results.

Workup

  1. customThe reaction product was purified

Sources & evidence

ORD record
ord-7e80ff8d705f4e73aca981bb4201c41f
Source dataset
uspto-grants-1993_11
Patent number
US05262420

Reaction notes

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