Ethylene Glycol → HCID 54120303, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 1 g (4.7 mM) of [5-(3-thienyl)tetrazol-1-yl] acetic acid in 5 ml of ethylene glycol was added 0.5 ml of sulfuric acid. After the addition, the mixture was stirred at 90° C. for 2.5 hrs. The mixture was then poured into ice-water and the precipitated crystal was filtered off, washed with water and recrystrallized from ethyl alcohol, to give 620 mg (yield 50%) of [5-(3-thienyl)tetrazol-1-yl] acetic acid 2-hydroxyethyl ester.

Provenance & Evidence