HRID257581

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID19783209

未命名化合物

结构：CCCCC(=O)C(Cc1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1F)C(C#N)=NOC

HCID54181722

未命名化合物

PRODUCTS

生成物

结构：CCCCc1nn(-c2cc(C(=O)OCC)ccc2C(F)(F)F)c(C#N)c1Cc1ccc(-c2ccccc2S(N)(=O)=O)cc1F

HCID19783179

未命名化合物

PROCEDURE

实验过程

The title compound is prepared by reaction of 3-[[2'-(N-t-butylsulfamoyl)-3-fluorobiphenyl-4-yl]methyl]-2-methoxyimino-4-oxooctanenitrile (from Step J) with ethyl 3-hydrazino-4-(trifluoromethyl)benzoate hydrochloride (from Step E) according to the procedure of Example 1, Step G.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b9c2907333554f4db901efcabb4d0788
来源数据集: uspto-grants-1993_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05262412
来源说明: uspto-grants-1993_11

反应 SMILES

C([NH:5][S:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH:22]([C:29](=O)[CH2:30][CH2:31][CH2:32][CH3:33])[C:23](=NOC)[C:24]#[N:25])=[C:17]([F:35])[CH:16]=1)(=[O:8])=[O:7])(C)(C)C.Cl.[NH:37]([C:39]1[CH:40]=[C:41]([CH:47]=[CH:48][C:49]=1[C:50]([F:53])([F:52])[F:51])[C:42]([O:44][CH2:45][CH3:46])=[O:43])[NH2:38]>>[CH2:30]([C:29]1[C:22]([CH2:21][C:18]2[CH:19]=[CH:20][C:15]([C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=3[S:6](=[O:8])(=[O:7])[NH2:5])=[CH:16][C:17]=2[F:35])=[C:23]([C:24]#[N:25])[N:37]([C:39]2[CH:40]=[C:41]([C:42]([O:44][CH2:45][CH3:46])=[O:43])[CH:47]=[CH:48][C:49]=2[C:50]([F:51])([F:52])[F:53])[N:38]=1)[CH2:31][CH2:32][CH3:33]