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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 257581Erstellt: 25. Oktober 2026

Ethyl 3-Hydrazino-4-(trifluoromethyl)benzoate hydrochloride → 3-n-Butyl-1-[5-(ethoxycarbonyl)-2-(trifluoromethyl)phenyl]-4-[(3-fluoro-2'-sulfamoylbiphenyl-4-yl)methyl]-1H-pyrazole-5-carbonitrile

https://huagongshe.com/reaction/257581

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktEthyl 3-Hydrazino-4-(trifluoromethyl)benzoate hydrochlorideHCID 19783209—
Edukt3-[[2'-(N-t-butylsulfamoyl)-3-fluorobiphenyl-4-yl]methyl]-2-methoxyimino-4-oxooctanenitrileHCID 54181722—
Produkt3-n-Butyl-1-[5-(ethoxycarbonyl)-2-(trifluoromethyl)phenyl]-4-[(3-fluoro-2'-sulfamoylbiphenyl-4-yl)methyl]-1H-pyrazole-5-carbonitrileHCID 19783179—

Reaktionsschritte

The title compound is prepared by reaction of 3-[[2'-(N-t-butylsulfamoyl)-3-fluorobiphenyl-4-yl]methyl]-2-methoxyimino-4-oxooctanenitrile (from Step J) with ethyl 3-hydrazino-4-(trifluoromethyl)benzoate hydrochloride (from Step E) according to the procedure of Example 1, Step G.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05262412
Quelldatensatzuspto-grants-1993_11
ORD IDord-b9c2907333554f4db901efcabb4d0788
Quellennotizuspto-grants-1993_11