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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 257746Erstellt: 25. Oktober 2026

4-Bromobutyryl chloride → 8-Chloro-5-(4-diethylamino-butyryl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one

https://huagongshe.com/reaction/257746

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-Bromobutyryl chlorideHCID 70225—
Edukt8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-oneHCID 3653116—
Produkt8-Chloro-5-(4-diethylamino-butyryl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-oneHCID 10667837—

Reaktionsschritte

The 5-(5-bromobutyryl)-8-chloro-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one, used as starting material, is synthesized similarly to the starting material described in Example 1 from 8-chloro-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-one and 4-bromobutyryl chloride. The yield is 83.1% of the theoretical yield and the melting point is 176°-177° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05264432
Quelldatensatzuspto-grants-1993_11
ORD IDord-d3b24c7feeb842ad93fc96aa34fb579e
Quellennotizuspto-grants-1993_11