Maleic Acid → HCID 67760077, compound

Participants

Reaction Steps

2.48 g (11.9 g mmoles) of 2-isopropylamino-4-methyl-5-methoxycarbonylpyrimidine and 1.38 g (11.9 mmoles) of maleic acid were dissolved in a mixture of 20 ml of ethanol and 20 ml of chloroform, and the solution was stirred for 3 hours. The solvents were evaporated, and ether was added for crystallization at 0° C. The desired product was obtained in an amount of 3.21 g (yield 83%) as pale yellow crystals.

Provenance & Evidence