反应详情

温度

50 °C

To a solution of sodium (210 mg, 9 mmol) in 2-(2-methoxyethoxy)ethanol (10 ml) was added 3-(4-chloro-1,2,5-thiadiazol-3-yl)pyridine (590 mg, 3 mmol). The mixture was stirred at 50° C. for 4 h and evaporated. The residue was dissolved in water and extracted with ether. The combined organic phases were dried and evaporated to give the title compound.

1. customevaporated
2. dissolutionThe residue was dissolved in water
3. extractionextracted with ether
4. customThe combined organic phases were dried
5. customevaporated