HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 3-(3-Amino-1,2,5-oxadiazol-4-yl)-1-methylpyridinium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 4-Pyridin-3-yl-1,2,5-oxadiazol-3-amine | HCID 1415523 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-(3-Amino-1,2,5-oxadiazol-4-yl)-1-methylpyridinium iodide | HCID 19075322 | — |
Reaction Steps
To a solution of 3-(4-amino-1,2,5-oxadiazol-3-yl)pyridine (870 mg, 5.3 mmol) in acetone (20 ml) was added methyl iodide (990 μl , 16 mmol) and the reaction mixture was stirred overnight at room temperature. The title compound precipitated and was collected by filtration (1.1 g, 69%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05264444 |
| Source dataset | uspto-grants-1993_11 |
| ORD ID | ord-e3c36da1faa84b0c80ac9aadfa4d4ba8 |
| Source note | uspto-grants-1993_11 |