Sodium Hydroxide → Sodium 2-chlorohypoxanthine hydrate

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Reaction Steps

In order to prepare the sodium salt of 2-chlorohypoxanthine in highly pure form, 2-chloro-hypoxanthine-hydrochloride-monohydrate is suspended in water. Whilst cooling, the pH is adjusted to a value in the range from 9 to 10, preferably, 9.5 to 10, and more preferably, 9.7, using an aqueous solution of an inorganic base, preferably a solution of an alkali metal hydroxide and more preferably using concentrated sodium hydroxide solution.

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