Ammonium Hydroxide → alpha-Amino-9H-xanthene-9-acetic acid

HRID 258190Notes

Reaction equation

HRID 258190 reaction equation
Cl.[NH2:2][CH:3]([CH:7]1[C:20]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[O:14][C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:4]([OH:6])=[O:5].[OH-].[NH4+]>O>[NH2:2][CH:3]([CH:7]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:13]=2[O:14][C:15]2[C:20]1=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:4]([OH:6])=[O:5]

Participants

4

Reactant 2

HCID 14923Ammonium HydroxideHCID 67805111alpha-Amino-9H-xanthene-9-acetic acid hydrochloride

Product 1

HCID 9816503alpha-Amino-9H-xanthene-9-acetic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

α-Amino-9H-xanthene-9-acetic acid hydrochloride is dissolved in water and the pH of the solution is adjusted with dilute ammonium hydroxide solution to pH 7. The precipitate is collected by filtration, washed with water, boiled with water for a short time, cooled to room temperature, and collected to afford the title compound.

Workup

  1. filtrationThe precipitate is collected by filtration
  2. washwashed with water
  3. customcollected

Sources & evidence

ORD record
ord-554525d0fffa4cb78e494cfa3229e3a3
Source dataset
uspto-grants-1993_11
Patent number
US05264577

Reaction notes

Loading…