Glycine → HCID 19737117, compound

Participants

Reaction Steps

From the first aliquot taken at 0.5 h, two new amino aids were noted upon amino acid analysis. A small peak appeared at 15.6 min, just after the glycine peak. The other was a large, sharp peak at 22.5 minutes. By three hours, the peak at 22.5 minutes, corresponding to the expected amino acid reached a maximum at about 10% of the glycine peak and then slowly decreased while the peak at 15.6 minutes increased slightly in intensity. The amino acid eluting at 15.6 min is the product from slow hydrolysis of the formate ester in the reaction medium. The structure corresponds to α-amino-β-hydroxy-6-hydroxyhexanoic acid.

Provenance & Evidence