Glycine → 3-Furan-2-ylserine

HRID 258224Notes

Reaction equation

HRID 258224 reaction equation
[NH2:1][CH2:2][C:3]([OH:5])=[O:4].[O:6]1[CH:10]=[CH:9][CH:8]=[C:7]1[CH:11]=[O:12]>>[NH2:1][CH:2]([CH:11]([OH:12])[C:7]1[O:6][CH:10]=[CH:9][CH:8]=1)[C:3]([OH:5])=[O:4]

Participants

3

Reactant 2

HCID 750GlycineHCID 7362Furfural

Product 1

HCID 1106593-Furan-2-ylserine

Procedure

The substrate solution was prepared by dissolving glycine (14.0 mg, 0.186 mmol) and furaldehyde (15.5 μL, 0.187 mmol) in buffer (10.0 mL). When 360 μL of this was added to the enzyme solution (0.2 mg SHMT in 40 μL), the concentration of each substrate was 17 mM.

Workup

  1. customThe substrate solution was prepared
  2. additionWhen 360 μL of this was added to the enzyme solution (0.2 mg SHMT in 40 μL)

Sources & evidence

ORD record
ord-216c4a504fe3464fafbe03ca23303fa5
Source dataset
uspto-grants-1993_11
Patent number
US05266468

Reaction notes

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