5-(4-Hydroxybenzyl)thiazolidine-2,4-dione → HCID 22288675, compound

HRID 258270Notes

Reaction equation

HRID 258270 reaction equation
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:4]=[C:5]([CH:9]([O:14][CH3:15])[CH2:10][N:11]=[C:12]=[O:13])[CH:6]=[CH:7][CH:8]=1.[OH:18][C:19]1[CH:24]=[CH:23][C:22]([CH2:25][CH:26]2[S:30][C:29](=[O:31])[NH:28][C:27]2=[O:32])=[CH:21][CH:20]=1>C1C=CC=CC=1.O1CCCC1>[F:1][C:2]([F:16])([F:17])[C:3]1[CH:4]=[C:5]([CH:9]([O:14][CH3:15])[CH2:10][NH:11][C:12]([O:18][C:19]2[CH:24]=[CH:23][C:22]([CH2:25][CH:26]3[S:30][C:29](=[O:31])[NH:28][C:27]3=[O:32])=[CH:21][CH:20]=2)=[O:13])[CH:6]=[CH:7][CH:8]=1

Participants

5

Reactant 2

HCID 101983975-(4-Hydroxybenzyl)thiazolidine-2,4-dioneHCID 19013421HCID 19013421, compound

Product 1

HCID 22288675HCID 22288675, compound

Reagents, catalysts & solvents 2

HCID 241BenzeneSolventHCID 8028TetrahydrofuranSolvent

Procedure

A solution containing 1.5 g of the compound prepared in stage A in 10 ml of benzene is added to a solution containing 1.4 g of 5-[(4-hydroxyphenyl)methyl]-2,4-thiazolidinedione in 5 ml of tetrahydrofuran.

Workup

  1. additionis added to a solution

Sources & evidence

ORD record
ord-ff976e88bf994cb2b3b14e4644bd4dea
Source dataset
uspto-grants-1993_11
Patent number
US05266582

Reaction notes

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