Toluene → 6-Diethylphosphono-3-methyl-2,4-hexadienal dioxolane

HRID 258398Notes

Reaction equation

HRID 258398 reaction equation
[P:1]([O:8][CH2:9][CH3:10])([O:5]CC)[O:2][CH2:3][CH3:4].Br[CH:12]1[O:16][CH2:15][CH2:14][O:13]1.[C:17]1([CH3:23])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[O:13]1[CH2:14][CH2:15][O:16][CH2:12]1.[CH2:9]([O:8][P:1]([CH2:20][CH:19]=[CH:18][C:17]([CH3:23])=[CH:22][CH:21]=[O:13])([O:2][CH2:3][CH3:4])=[O:5])[CH3:10]

Participants

4

Reactant 3

HCID 1140Toluene2×HCID 31215Triethyl phosphiteHCID 143725662-Bromo-1,3-dioxolane

Product 1

HCID 867474006-Diethylphosphono-3-methyl-2,4-hexadienal dioxolane

Procedure

Triethyl phosphite (2.56 g, 15.44 mmol) in dry toluene (10 ml) and bromodioxolane (H) (3 g, 12.87 mmol) in toluene (10 ml) were introduced in succession into a 50-ml two-necked flask fitted with a thermometer and a condenser.

Workup

  1. customfitted with a thermometer and a condenser

Sources & evidence

ORD record
ord-cd82384b784d4ebca17d40c0c996320e
Source dataset
uspto-grants-1993_11
Patent number
US05266708

Reaction notes

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