反应详情

A mixture of 119 parts of 4'-chloro-2'-fluoroacetanilide in 475 parts of ethanol and 200 parts of 37% hydrochloric acid was refluxed for 17 hours and the solvent was removed under reduced pressure of 300 mm Hg to yield the moist, solid hydrochloride salt of 4-chloro-2-fluoroaniline.

1. temperaturewas refluxed for 17 hours
2. customthe solvent was removed under reduced pressure of 300 mm Hg