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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 258574Generated: October 29, 2026

Ammonia → HCID 20365142, compound

https://huagongshe.com/reaction/258574

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantLithiumHCID 3028194—
ReactantHCID 20365138HCID 20365138—
ProductHCID 20365142HCID 20365142—

Reaction Steps

A sample of 1-methyl-α-(2-methylphenyl)-3-pyrrolidine-ethanol (23 α, 0.105 moles) is subjected to Birch reduction in 500 ml liquid ammonia with 7 g (1 mole) of lithium to give a quantitative yield of 3-(3,6-dihydro-2-methylphenethyl)-N-methylpyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04033971
Source datasetuspto-grants-1977_07
ORD IDord-c70862bbdeb14932b279b5d1b922d579
Source noteuspto-grants-1977_07