3-Amino-1,2-propanediol → HCID 178484469, compound

HRID 258660Notes

Reaction equation

HRID 258660 reaction equation
Cl.OC(CO)[CH2:4][NH:5][C:6]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[N:17]=[C:8]([C:9]([NH:11][C:12]2[NH:16][N:15]=[N:14][N:13]=2)=[O:10])[CH:7]=1.[Cl:26]C1C2C(=CC=CC=2)N=[C:29]([C:30](NC2NN=NN=2)=[O:31])C=1.NCC(O)CO>>[ClH:26].[OH:31][CH2:30][CH2:29][N:5]([CH3:4])[C:6]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[N:17]=[C:8]([C:9]([NH:11][C:12]2[NH:16][N:15]=[N:14][N:13]=2)=[O:10])[CH:7]=1

Participants

4

Reactant 3

HCID 735613-Amino-1,2-propanediolHCID 178479730HCID 178479730, compoundHCID 178522680HCID 178522680, compound

Product 1

HCID 178484469HCID 178484469, compound

Procedure

In a similar way, 4(2,3-Dihydroxypropylamino)-N(1H-tetrazol-5-yl)quinaldamide, hydrochloride, m.p. 264° (d) was prepared from 4-chloro-N (1H-tetrazol-5-yl)quinaldamide (Example 2) and 3-amino-1,2-propanediol.

Sources & evidence

ORD record
ord-4cbe4d616b384d88b811a7d83447f435
Source dataset
uspto-grants-1977_07
Patent number
US04034075

Reaction notes

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