HCID 54109521, compound → HCID 21426444, compound

Participants

Reaction Steps

Ethyl (2-mesyl-imidazol-1-yl)-acetate (21.4 g.) in 4N sulphuric acid (50 cc.) is heated under reflux for 11/2 hours. A product crystallises on cooling. Crystallisation is completed by keeping the mixture in a bath of ice and water for 5 hours. After filtration, crystals (13.7 g.) which melt at 216- 217° C. are obtained. Recrystallisation from water (110 cc.) gives (2-mesylimidazol-1-yl)-acetic acid (12.7 g.), melting at 218- 219° C.

Provenance & Evidence