Potassium Hydroxide → 4-Benzenesulphonamido-1-(4-phenylbutyl)piperidine

HRID 258721Notes

Reaction equation

HRID 258721 reaction equation
[C:1]1([S:7]([NH:10][CH:11]2[CH2:16][CH2:15][N:14]([CH2:17][CH2:18][CH2:19][C:20]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=O)[CH2:13][CH2:12]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.O.NN.[OH-].[K+]>>[C:1]1([S:7]([NH:10][CH:11]2[CH2:12][CH2:13][N:14]([CH2:17][CH2:18][CH2:19][CH2:20][C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH2:15][CH2:16]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 14797Potassium HydroxideHCID 24654Hydrazine hydrate (1:1)HCID 536955074-Benzenesulphonamido-1-(4-phenyl-4-oxobutyl)piperidine

Product 1

HCID 541332624-Benzenesulphonamido-1-(4-phenylbutyl)piperidine

Procedure

4-Benzenesulphonamido-1-(4-phenyl-4-oxobutyl)piperidine may be reacted with hydrazine hydrate and potassium hydroxide under Wolff-Kishner reaction conditions to give the title compound.

Sources & evidence

ORD record
ord-a217e79036eb4b8ca16a94696223fd34
Source dataset
uspto-grants-1977_07
Patent number
US04034098

Reaction notes

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