huagongshe.com
HRID25875

反应详情

EQUATION

反应方程式

HRID 25875 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)CC(=O)CC(=O)OC
HCID74591

Dimethyl 3-oxoglutarate

C7H10O5

结构：CCN(CC)c1ccc(C=O)c(O)c1
HCID87293

4-(Diethylamino)salicylaldehyde

C11H15NO2

PRODUCTS

生成物

1
结构：CCN(CC)c1ccc2cc(C(=O)CC(=O)OC)c(=O)oc2c1
HCID3326307

2H-1-Benzopyran-3-propanoic acid, 7-(diethylamino)-β,2-dioxo-, methyl ester

C17H19NO5

PROCEDURE

实验过程

A solution of 1.93 g 4-diethylaminosalicylaldehyde, 1.80 g. dimethyl 1,3-acetone dicarboxylate in 10 ml. alcohol containing 10 drops piperidine was heated under reflux on a steam bath for 2 hours. After chilling in the freezer, the product was collected and recrystallized from a mixture of alcohol and acetonitrile. Yield 2.6 g (82%).

WORKUP

后处理

  1. temperatureunder reflux on a steam bath for 2 hours
  2. temperatureAfter chilling in the freezer
  3. customthe product was collected
  4. customrecrystallized from a mixture of alcohol and acetonitrile