反应详情

A mixture of 0.65 g ethyl nicotinoylacetate, 0.5 g 2-hydroxyanisaldehyde and 10 ml alcohol was heated on a steam bath until solution was attained. Five drops of piperdine were added and heating was continued. After several minutes the reaction mixture solidified. An additional 10 ml of alcohol were added and the reaction mixture heated another 15 minutes. After cooling, the solid was collected and recrystallized twice from a mixture of alcohol and acetonitrile.

1. temperaturewas heated on a steam bath until solution
2. temperatureheating
3. waitAfter several minutes the reaction mixture solidified
4. temperaturethe reaction mixture heated another 15 minutes
5. temperatureAfter cooling
6. customthe solid was collected
7. customrecrystallized twice from a mixture of alcohol and acetonitrile