Ammonium Hydroxide → HCID 21391786, compound

HRID 258939Notes

Reaction equation

HRID 258939 reaction equation
[C:1]1([C:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14]3([C:17](Cl)=[O:18])[CH2:16][CH2:15]3)=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1.[OH-].[NH4+:21]>>[C:1]1([C:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14]3([C:17]([NH2:21])=[O:18])[CH2:16][CH2:15]3)=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 14923Ammonium HydroxideHCID 21391742HCID 21391742, compound

Product 1

HCID 21391786HCID 21391786, compound

Procedure

A mixture of 4.2 parts of 1-[p-(2-thenoyl)phenyl]cyclopropanecarbonyl chloride and 50 parts of ammonium hydroxide is stirred for 3 hours. The precipitated product is filtered off, washed with water, dried and crystallized from 2-propanol, yielding 2 parts of 1-[p-(2-thenoyl)phenyl]cyclopropanecarboxamide; mp. 173.7° C (dec.).

Workup

  1. filtrationThe precipitated product is filtered off
  2. washwashed with water
  3. customdried
  4. customcrystallized from 2-propanol

Sources & evidence

ORD record
ord-47676453d36c43468ddef0bb8704d979
Source dataset
uspto-grants-1977_07
Patent number
US04035376

Reaction notes

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