Methyl vinyl ketone → HCID 14663656, compound

HRID 258950Notes

Reaction equation

HRID 258950 reaction equation
[CH:1](=[O:8])[CH2:2][CH2:3][C:4]#[C:5][CH2:6][CH3:7].[CH:9]([C:11]([CH3:13])=[O:12])=[CH2:10].C(N(CC)CC)C>>[CH3:13][C:11](=[O:12])[CH2:9][CH2:10][C:1](=[O:8])[CH2:2][CH2:3][C:4]#[C:5][CH2:6][CH3:7]

Participants

4

Reactant 3

HCID 6570Methyl vinyl ketoneHCID 8471TriethylamineHCID 18330928Hept-4-ynal

Product 1

HCID 14663656HCID 14663656, compound

Procedure

22.0 g (0.2 mol) of hept-4-in-1-al, 14 g (0.2 mol) of methyl vinyl ketone, 5.4 g (0.02 mol) of Cat. 1 and 12.6 g (0.12 mol) of triethylamine are brought together in the manner described in Example 26. After 12 hours' reaction time at a surrounding temperature of 80° C in a nitrogen atmosphere, the mixture is worked up in the manner described in Example 21. On subsequent fractionation, undec-8-ine-2,5-dione is obtained.

Workup

  1. customAfter 12 hours' reaction time at a surrounding temperature of 80° C in a nitrogen atmosphere

Sources & evidence

ORD record
ord-b017c01ef9fb46c99c4f73a73a08d6cd
Source dataset
uspto-grants-1977_07
Patent number
US04035395

Reaction notes

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