反应详情

2-Chloro-3-(p-methoxyphenyl)-2-cyclobuten-1-one (17.4 g., 0.084 mole), triethylamine (11.7 ml., 0.084 mole), and 2.1 g. of 10% Pd/C in 300 ml. of 10% aqueous methanol is shaken under H2 (50 psi) until reduction is complete (30 min). The mixture is filtered and the filtrate evaporated. An ether solution of the residue is washed (water), dried (MgSO4), and evaporated to give 15.4 g. of an oil which is chromatographed on alumina using benzene.

1. custom(30 min)
2. filtrationThe mixture is filtered
3. customthe filtrate evaporated
4. washAn ether solution of the residue is washed (water)
5. dry with materialdried (MgSO4)
6. customevaporated
7. customto give 15.4 g
8. customof an oil which is chromatographed on alumina