Sodium Sulfate → HCID 21425202, compound

HRID 258969Notes

Reaction equation

HRID 258969 reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].[C:7]([C:13]1[CH:20]=[CH:19][C:16]([CH2:17][OH:18])=[CH:15][CH:14]=1)(=[O:12])[C:8]([CH3:11])([CH3:10])[CH3:9].S([O-])([O-])(=O)=O.[Na+].[Na+]>O1CCCC1>[C:8]([CH:7]([OH:12])[C:13]1[CH:14]=[CH:15][C:16]([CH2:17][OH:18])=[CH:19][CH:20]=1)([CH3:11])([CH3:9])[CH3:10]

Participants

5

Reactant 3

HCID 24436Sodium SulfateHCID 21226445Aluminium lithium hydrideHCID 21425203HCID 21425203, compound

Product 1

HCID 21425202HCID 21425202, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

A suspension of 2.7 grams (0.070 mole) of lithium aluminum hydride in 170 milliliters of dry tetrahydrofuran is cooled to 0° and treated by dropwise addition with 6.7 grams (0.035 mole) of p-pivaloyl benzyl alcohol in 70 milliliters of dry tetrahydrofuran. The resulting mixture is stirred for 5 hours at room temperature, and then cooled to 0° C. and treated by dropwise addition with saturated sodium sulfate solution. The mixture is filtered and the filter cake is washed thoroughly with tetrahydrofuran. The tetrahydrofuran is dried over magnesium sulfate, filtered and evaporated to give α-t-butyl-p-xylene-α,α'-diol, m.p. 91° to 95° C.

Workup

  1. temperatureis cooled to 0°
  2. temperaturecooled to 0° C.
  3. filtrationThe mixture is filtered
  4. washthe filter cake is washed thoroughly with tetrahydrofuran
  5. dry with materialThe tetrahydrofuran is dried over magnesium sulfate
  6. filtrationfiltered
  7. customevaporated

Sources & evidence

ORD record
ord-d1498893abb44cad948ecef5aca40f4e
Source dataset
uspto-grants-1977_07
Patent number
US04035427

Reaction notes

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