反应详情

温度

10 °C

To a 4-neck round bottom flask equipped with a thermometer, a condensor and two addition funnels was charged 50 ml of tetrahydrofuran and 50 ml of water and the solution was cooled to 10° C. To this well stirred solution was added together in the two addition funnels bromine (0.20 mole) and 1(2-furyl)-1-ethanol (0.09 mole). The temperature of the reaction was maintained at 15° C. throughout the double addition. The reaction mixture was then heated to 75° C. for 10 hours. Maltol was isolated by the procedure of Example 1 (53% yield).

1. customTo a 4-neck round bottom flask equipped with a thermometer
2. additiona condensor and two addition funnels
3. temperatureThe temperature of the reaction was maintained at 15° C. throughout the double addition
4. temperatureThe reaction mixture was then heated to 75° C. for 10 hours