反应详情

To a cooled solution of 158.3 grams of 1-decanol in 1.0 liter of collidine is added dropwise 126 grams of mesyl chloride. The resulting mixture is stirred at room temperature for 1.5 hours and then poured onto ice. The reaction mixture is extracted with ether and the ether extracts are washed with 10% hydrochloric acid. The ether extracts are combined, dried over anhydrous sodium sulfate, and the solvent removed under reduced pressure to leave an oil which solidifies upon cooling. The oil is dissolved in n-hexane and cooled to yield as crystals, decyl methylsulfonate.

1. additionpoured onto ice
2. extractionThe reaction mixture is extracted with ether
3. washthe ether extracts are washed with 10% hydrochloric acid
4. dry with materialdried over anhydrous sodium sulfate
5. customthe solvent removed under reduced pressure
6. customto leave an oil which
7. temperatureupon cooling
8. temperaturecooled