Hydrochloric Acid → HCID 12930913, compound

Participants

Reaction Conditions

Reaction Steps

To 30.0 grams of 1-ethoxycarbonyl-4-pentadecylpiperazine is added 200 ml. of concentrated hydrochloric acid and the mixture refluxed for 48 hours. The mixture is cooled to approximately 0° C. and the resultant solid filtered and suction-dried. The solid is suspended in water and 10 ml. of 50% sodium hydroxide added. The solution is then extracted with ethyl ether. Removal of the ethyl ether leaves, as an oil, 1-pentadecylpiperazine.

Provenance & Evidence