Hydrochloric Acid → HCID 12930913, compound

HRID 259069Notes

Reaction equation

HRID 259069 reaction equation
C(OC([N:6]1[CH2:11][CH2:10][N:9]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[CH2:8][CH2:7]1)=O)C.Cl>>[CH2:12]([N:9]1[CH2:8][CH2:7][NH:6][CH2:11][CH2:10]1)[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 21423023HCID 21423023, compound

Product 1

HCID 12930913HCID 12930913, compound

Conditions

Temperature
0 °C

Procedure

To 30.0 grams of 1-ethoxycarbonyl-4-pentadecylpiperazine is added 200 ml. of concentrated hydrochloric acid and the mixture refluxed for 48 hours. The mixture is cooled to approximately 0° C. and the resultant solid filtered and suction-dried. The solid is suspended in water and 10 ml. of 50% sodium hydroxide added. The solution is then extracted with ethyl ether. Removal of the ethyl ether leaves, as an oil, 1-pentadecylpiperazine.

Workup

  1. filtrationthe resultant solid filtered
  2. customsuction-dried
  3. additionof 50% sodium hydroxide added
  4. extractionThe solution is then extracted with ethyl ether
  5. customRemoval of the ethyl ether

Sources & evidence

ORD record
ord-6dbba3ba1c3849b78eba98e7e8ad017b
Source dataset
uspto-grants-1977_07
Patent number
US04036828

Reaction notes

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