Thionyl Chloride → HCID 21423938, compound

HRID 259269Notes

Reaction equation

HRID 259269 reaction equation
[CH2:1]([S:13][CH2:14][CH:15](O)[CH2:16][N:17]1[CH:21]=[CH:20][N:19]=[CH:18]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].S(Cl)([Cl:25])=O>ClCCl>[ClH:25].[Cl:25][CH:15]([CH2:14][S:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])[CH2:16][N:17]1[CH:21]=[CH:20][N:19]=[CH:18]1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 21423825HCID 21423825, compound

Product 1

HCID 21423938HCID 21423938, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1-[3'-n-dodecylthio-2'-hydroxypropyl]imidazole (1.63 g.) in 20 ml. of dichloromethane and 2 ml. of thionyl chloride are stirred for 2 hours at room temperature. Thereafter, the reaction mixture is evaporated to dryness to yield 1-[2'-chloro-3'-(n-dodecylthio)propyl]imidazole hydrochloride as a gum.

Workup

  1. customThereafter, the reaction mixture is evaporated to dryness

Sources & evidence

ORD record
ord-80a8cdc913ff45e9b0fde9130ce02c9c
Source dataset
uspto-grants-1977_07
Patent number
US04036974

Reaction notes

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