Oxalic Acid → HCID 21423889, compound

HRID 259271Notes

Reaction equation

HRID 259271 reaction equation
[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH:7]1([S:13][CH:14]([CH2:21][S:22][CH:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)[CH2:15][N:16]2[CH:20]=[CH:19][N:18]=[CH:17]2)[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1>>[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH:7]1([S:13][CH:14]([CH2:21][S:22][CH:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)[CH2:15][N:16]2[CH:20]=[CH:19][N:18]=[CH:17]2)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 971Oxalic AcidHCID 21423875HCID 21423875, compound

Product 1

HCID 21423889HCID 21423889, compound

Procedure

Oxalic acid is added dropwise to a stirred solution of 3.2 g. of 1-[2',3'-bis(cyclohexylthio)propyl]imidazole in 300 ml. of anhydrous ether until precipitation is complete. The product is filtered off, washed with ether, air dried and recrystallized from ethyl acetate to yield 1-[2',3'-bis(cyclohexylthio)propyl]imidazole oxalate, m.p. 85.5°-88.5° C.

Workup

  1. customof anhydrous ether until precipitation
  2. filtrationThe product is filtered off
  3. washwashed with ether, air
  4. customdried
  5. customrecrystallized from ethyl acetate

Sources & evidence

ORD record
ord-285fa3e8b6994c05a7dbc8d49a31c4f1
Source dataset
uspto-grants-1977_07
Patent number
US04036974

Reaction notes

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