Nitric Acid → HCID 21423753, compound

HRID 259281Notes

Reaction equation

HRID 259281 reaction equation
[N+:1]([O-:4])([OH:3])=[O:2].[CH:5]([O:8][CH2:9][CH:10]([S:17][C:18]1[C:23]([Cl:24])=[C:22]([Cl:25])[C:21]([Cl:26])=[C:20]([Cl:27])[C:19]=1[Cl:28])[CH2:11][N:12]1[CH:16]=[CH:15][N:14]=[CH:13]1)([CH3:7])[CH3:6]>>[N+:1]([O-:4])([OH:3])=[O:2].[CH:5]([O:8][CH2:9][CH:10]([S:17][C:18]1[C:19]([Cl:28])=[C:20]([Cl:27])[C:21]([Cl:26])=[C:22]([Cl:25])[C:23]=1[Cl:24])[CH2:11][N:12]1[CH:16]=[CH:15][N:14]=[CH:13]1)([CH3:7])[CH3:6]

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 21423754HCID 21423754, compound

Product 1

HCID 21423753HCID 21423753, compound

Procedure

Nitric acid (70%; d = 1.42) is added dropwise to a stirred solution of 2.0 g. of 1-[3'-isopropoxy-2'-(pentachlorophenylthio)propyl]imidazole in 30 ml. of anhydrous ether until precipitation was complete. The product was filtered off, washed with ether, air dried, and recrystallized from ethyl acetate to yield 1-[3'-isopropoxy-2'-(pentachlorophenylthio)propyl]imidazole nitrate.

Workup

  1. customof anhydrous ether until precipitation
  2. filtrationThe product was filtered off
  3. washwashed with ether, air
  4. customdried
  5. customrecrystallized from ethyl acetate

Sources & evidence

ORD record
ord-29e2f054d865433092fea4e63110bd87
Source dataset
uspto-grants-1977_07
Patent number
US04036973

Reaction notes

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