HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 4-Amino-5,6-dihydro-1-benzothiophen-7(4H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4,5,6,7-Tetrahydro-7-oxobenzo[b]thiophen-4-amine hydrochloride | HCID 23347795 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-Amino-5,6-dihydro-1-benzothiophen-7(4H)-one | HCID 23347796 | — |
Reaction Steps
The free amine is obtained by neutralizing the amine hydrochloride in water with sodium hydroxide solution. It is separated by extraction with CHCl3 and removal of the CHCl3 in vacuo affords 4,5,6,7-tetrahydro-7-oxobenzo[b]thiophen-4-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04036979 |
| Source dataset | uspto-grants-1977_07 |
| ORD ID | ord-d354b11bc4894fd8a8ebc99a9b71a2f8 |
| Source note | uspto-grants-1977_07 |