Hydrochloric Acid → HCID 21421694, compound

HRID 259414Notes

Reaction equation

HRID 259414 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][C:12]([CH3:15])([CH3:14])[NH:11][C:10]([CH3:17])([CH3:16])[CH2:9]2)=[CH:4][CH:3]=1.[ClH:18]>CO>[ClH:18].[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:9][C:10]([CH3:17])([CH3:16])[NH:11][C:12]([CH3:15])([CH3:14])[CH2:13]2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21421695HCID 21421695, compound

Product 1

HCID 21421694HCID 21421694, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

6 Parts of 4(4'-hydroxyphenyl)-2,2,6,6-tetramethylpiperidine were dissolved in methanol and treated with excess concentrated hydrochloric acid. The solution was warmed at 50° for 15 minutes and then evaporated to dryness under reduced pressure. The solid residue was crystallised from a chloroform -methanol-petroleum (b.p. 60°-80° C.) mixture to afford 6.0 parts of the desired product melting at > 300° and having the following elemental analysis.

Workup

  1. temperatureThe solution was warmed at 50° for 15 minutes
  2. customevaporated to dryness under reduced pressure
  3. customThe solid residue was crystallised from a chloroform -methanol-petroleum (b.p. 60°-80° C.) mixture

Sources & evidence

ORD record
ord-8d1842c9f32c42e48542538330811d37
Source dataset
uspto-grants-1977_07
Patent number
US04038280

Reaction notes

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