反应详情

To a mechanically stirred mixture of 83.2 g benzalacetophenone (0.3m), 1000 ml methanol and 120 ml 15% hydrogen peroxide was added 100 ml 2N sodium hydroxide solution, while maintaining the temperature below 30° by external cooling. After completed addition, the mixture was left standing at room temperature for 20 min. The crystalline precipitate was filtered off, washed with water and recrystallized from methanol. There were obtained 59.6 g 1,3-diphenyl-2,3-epoxy-1-propanone; m.p. 90° C.

1. temperaturewhile maintaining the temperature below 30° by external cooling
2. additionaddition
3. waitthe mixture was left
4. filtrationThe crystalline precipitate was filtered off
5. washwashed with water
6. customrecrystallized from methanol