Hydrogen Peroxide → HCID 178498666, compound

HRID 259517Notes

Reaction equation

HRID 259517 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7][CH2:8][C:9]1[N+:18]([O-:19])=[C:17]2[C:12]([CH:13]=[CH:14][CH:15]=[CH:16]2)=[N+:11]([O-:20])[C:10]=1[C:21]([O:23][CH3:24])=[O:22].[OH:25]S(O)(=O)=O.[O-][Mn](=O)(=O)=O.[K+].OO.[OH2:38]>CC(C)=O>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7]([CH2:8][C:9]1[N+:18]([O-:19])=[C:17]2[C:12]([CH:13]=[CH:14][CH:15]=[CH:16]2)=[N+:11]([O-:20])[C:10]=1[C:21]([O:23][CH3:24])=[O:22])(=[O:25])=[O:38]

Participants

7

Reactant 5

HCID 784Hydrogen PeroxideHCID 962WaterHCID 1118Sulfuric AcidHCID 516875Potassium PermanganateHCID 178498619HCID 178498619, compound

Product 1

HCID 178498666HCID 178498666, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

Methyl 3-[(2-pyridyl)-thiomethyl]-2-quinoxalinecarboxylate-1,4-dioxide (0.03 moles) in 60 ml of acetone was cooled to 0°-5° C. and 50 ml of 2N H2SO4 was added in one portion. This was followed by the dropwise addition of a solution of KMnO4 (0.04 moles) in 150 ml of water over a 20 minute period. The mixture was stirred for about 5 minutes at which time 4 ml of 30% H2O2 was added very carefully dropwise to decolorize the purple solution. The desired product, which had precipitated, was collected by filtration and washed with water. Yield, 8.12 grams (87%); m.p. 154° C. (dec.).

Workup

  1. additionwas added very carefully dropwise
  2. customThe desired product, which had precipitated
  3. filtrationwas collected by filtration
  4. washwashed with water
  5. customYield

Sources & evidence

ORD record
ord-ad4dd5c15e2b4d8ebf58c413fd8a2511
Source dataset
uspto-grants-1977_07
Patent number
US04038392

Reaction notes

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