反应详情

A solution of 1 g. of 2-(2-fluorophenyl)oxazolo[4,5-b]pyridine (from Example 6) in 10 ml. of acetic acid was treated with 2 ml. of 30% hydrogen peroxide and heated on the steam bath for 16 hours. After cooling the mixture was diluted with ice-water. The precipitate was collected and recrystallized from dioxane-ether to give 2-(2-fluorophenyl)oxazolo [4,5-b]pyridine-4-oxide, m.p. 214°-216° C.

1. temperatureAfter cooling the mixture
2. customThe precipitate was collected
3. customrecrystallized from dioxane-ether