Isopropylamine → HCID 53860405, compound

HRID 259601Notes

Reaction equation

HRID 259601 reaction equation
[CH2:1]([O:5][C:6]([NH:8][CH:9]=[CH:10][C:11]1[CH:21]=[CH:20][C:14]([O:15][CH2:16][CH:17]2[O:19][CH2:18]2)=[CH:13][CH:12]=1)=[O:7])[CH2:2][CH2:3][CH3:4].[CH:22]([NH2:25])([CH3:24])[CH3:23]>C(O)(C)C>[CH2:1]([O:5][C:6]([NH:8][CH:9]=[CH:10][C:11]1[CH:21]=[CH:20][C:14]([O:15][CH2:16][CH:17]([OH:19])[CH2:18][NH:25][CH:22]([CH3:24])[CH3:23])=[CH:13][CH:12]=1)=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 6363IsopropylamineHCID 53853551HCID 53853551, compound

Product 1

HCID 53860405HCID 53860405, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Analogously to the description in Example 2, 3.93 g (0.0135 mol) of 1-[p-(2-n-butoxycarbonylaminovinyl)-phenoxy]-2,3-epoxy-propane, on reaction with 1.22 ml (0.0142 mol) of isopropylamine in 50 ml of isopropanol, yield 1-[p-(2-n-butoxycarbonylaminovinyl)-phenoxy]-2-hydroxy-3-isopropylaminopropane of melting point of 125°-126° C. (from acetone-ether).

Sources & evidence

ORD record
ord-040c4f8b974e49bb8283d3da7c1f0398
Source dataset
uspto-grants-1977_07
Patent number
US04038414

Reaction notes

Loading…