Isopropylamine → HCID 54118625, compound

Participants

Reaction Steps

4.9 g (0.017 mol) of 1-[2-allyl-4-(2-methoxycarbonylaminovinyl)-phenoxy]-2,3-epoxy-propane are heated for 3 hours with a solution of 1.57 ml (0.018 mol) of isopropylamine in 100 ml of isopropanol to 80° C. under reflux. The mixture is then evaporated under reduced pressure and the resulting crude base is crystallised from acetone-ether. 1-[2-Allyl-4-(2-methoxycarbonylaminovinyl)-phenoxy]-2-hydroxy-3-isopropylamino-propane, of melting point 128°-129° C. is obtained.

Provenance & Evidence